Selected Publications

E. Ballinger, J. Mosior, T. Hartman, K. Burns-Huang, B. Gold, R. Morris, L. Goullieux, I. Blanc, J. Vaubourgeix, S. Lagrange, L. Fraisse, S. Sans, C. Couturier, E. Bacqué, K. Rhee, S. M. Scarry, J. Aubé, G. Yang, O. Ouerfelli, D. Schnappinger, T. R. Ioerger, C. A. Engelhart, J. A. McConnel, K. McAulay, A. Fay, C. Roubert, J. Sacchettini, C. Nathan. Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition. Science 363: eaau8959, 2019 Link

H. Yu, T. J. Lupoli, A. Kovach, X. Meng, G. Zhao, C. F. Nathan and H. Li. ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB. Proc. Natl. Acad. Sci. USA 115: E9560-E9569, 2018 Link

L. A. Kirkman, W. Zhan, J. Visone, A. Dziedziech, P. K. Singh, H. Fan, X. Tong, I. Bruzual, R. Hara, M. Kawasaki, T. Imaeda, R. Okamoto, K. Sato, M. Michino, E. Alvero, L. F. Guiang, L. Sanz, D. J. Mota, K. Fovindasamy, R. Wang, Y. Ling, P. K. Tumwebaze, G. Sukenick, L. Shi, J. Vendome, P. Bhanot, P. J. Rosenthal, K. Aso, M. A. Foley, R. A. Cooper, B. Kafsack, J. S. Doggett, C. F. Nathan and G. Lin. Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance. Proc. Natl. Acad. Sci. USA 115: E6863-E6870, 2018 Link

C. Nathan.  Kunkel Lecture:  Fundamental immunodeficienty and its correction.  J. Exp. Med. 214:  2175-2191, 2017   PDF

K. Saito, T. Warrier, S. Somersan-Karakaya, L. Kaminski, J. Mi, X. Jiang, S. Park, K. Shigyo, B. Gold, J. Roberts, E. Weber, W. R. Jacobs, Jr., and C. Nathan.  Rifamycin action on RNA polymerase in antibiotic tolerant Mycobacterium tuberculosis results in differentially detectable populations.  Proc. Natl. Acad. Sci. USA  114:  E4832-E4840, 2017   PDF